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Bioinformatician or Senior Bioinformatician in Computational Immunology

University of Oxford - Department of Biochemistry

Location: Oxford
Salary: £45,585 to £54,395 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 28th May 2024
Closes: 21st June 2024
Job Ref: 173084

Reporting to Associate Professor Rachael Bashford-Rogers as well as collaborators Dr Alex Clarke (Kennedy Institute of Rheumatology, KIR) and Prof Edward Vital (Leeds), the successful candidate will join the Immune-repertoire research group in the Department of Biochemistry. The post holder will be the lead in providing bioinformatics expertise to a multi-disciplinary team of clinicians and scientists in studying the immunobiology underlying the development of systemic lupus erythematosus (SLE) and related autoantibody-mediated diseases.

This exciting project involves the analysis and integration of single-cell multi-omics including scRNA-seq, CITE-SEQ, T and B cell repertoire, as well as CyTOF analysis of immunometabolic state on at-risk pre-SLE, SLE and healthy control samples to understand immune dynamics.

The post holder will benefit from opportunities to strengthen the groups collaborations with a variety of biologists and scientists in Oxford and internationally as well as collaborative environment in Biochemistry.

This full-time fixed-term post is funded by Versus Arthritis for up to 2 years in the first instance.

We would be willing to consider candidates with potential but less experience who are seeking a development opportunity, for which an initial appointment would be at grade 7 (£36,024 - £44,263 per annum), with the responsibilities adjusted accordingly. This would be discussed with applicants at interview/appointment where appropriate.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available (this is unlikely to be more than £45,585 per annum).

Your happiness and wellbeing at work matters to us, so we offer a range of family friendly and financial benefits including:

  • An excellent contributory pension scheme
  • 38 days annual leave
  • A comprehensive range of childcare services
  • Family leave schemes
  • Cycle loan scheme
  • Membership to a variety of social and sports clubs
  • Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

You will either hold a PhD/DPhil, or be near completion of a PhD or DPhil in a relevant scientific subject. You will have demonstrable experience in biostatics or bioinformatics, as well as experience in cellular immunology. You will have an ability to analyse and clearly present data to specialists and non-specialists alike and have research experience and a publication record. You will be required to supervise staff and junior members of a lab and be able to work in a team environment. You should be proficient in statistical programming languages such as R and/or Python, with experience in developing new and innovative bioinformatic techniques.

You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online

Only applications received before noon Friday 21st June 2024 can be considered, with interviews for shortlisted candidates to be held as soon as possible thereafter.

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