Research Fellow

About the role

The applicant will have the opportunity to join a new group that is being developed in collaboration with an established dynamic team at Gustave Roussy, France. The exciting program is part of a new Fight Kids Cancer grant, and aims at developing and evaluating novel therapeutic approaches to target aggressive transcription factors-driven sarcomas of unmet need of the children and young adult, using notably degrader-based (PROTAC, small molecule or antibody) approaches.

Your application should include a CV and a Cover Letter: In the Cover Letter please evidence the essential and desirable criteria in the Person Specification part of the Job Description. (By including a Cover Letter, you can leave blank the 'Why you have applied for this role' field in the application form, which is limited in the number of characters it will allow.)

Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.

This position is funded for 3 years in the first instance with possibility of extension.

PhD students who are in the last months of their project are also encouraged to apply, but should indicate in their application when they can join the group.

About you

Successful candidates must have A PhD (or close to completion) with relevant laboratory experience or an MSc. in Cancer Biology, Haematology or a related discipline (or close to completion) or higher degree.

The candidate should have a solid knowledge of molecular biology, protein chemistry and engineering, Ab structure, genome editing (CRISPR and lentival transfections notably), molecular cloning and cell culture. Experience in high-throughput screening using antibody, phage display, small molecule or DNA encoded libraries is desirable. This role will also benefit those who have experience in imaging (immunofluorescence), flow cytometry and bioinformatics (notably bulk and single-cell RNA-Seq analysis).

Willingness to perform in vivo experiments and bioinformatic analyses, and to undergo further training if required and skills in Multiparametric flow cytometry are desirable but not essential.

For rewards and benefits at UCL please visit: https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits

You can read more about our commitment to Equality, Diversity and Inclusion here: https://www.ucl.ac.uk/equality-diversity-inclusion/

Customer advert reference: B02-08446

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