Postdoctoral Researcher
University of Oxford - DCHB South Parks Road, Oxford OX1 3QU
| Location: | Oxford |
|---|---|
| Salary: | £38,674 to £46,913 per annum. A less experienced candidate may be appointed at Research Grade 6 (£34,982 to £40,855) per annum, with a commensurate adjustment in either the essential criteria, responsibilities or duties. |
| Hours: | Full Time |
| Contract Type: | Fixed-Term/Contract |
| Placed On: | 21st February 2025 |
|---|---|
| Closes: | 28th February 2025 |
| Job Ref: | 178267 |
We have a exciting opportunity for a Postdoctoral Researcher to join us. Sleep and circadian rhythm disruption (SCRD) is a significant burden on individuals with Parkinson’s disease (PD), impairing their quality of life and creating challenges for caregivers, often leading to institutionalization. This research project aims to assess the efficacy of two novel modulators of circadian rhythms in stabilizing SCRD and improving cognitive and mental health in mouse models of PD. The individual will be required to work within a team of four researchers and in collaboration with the spin-out company to evaluate the effect chronic dosing of circadian rhythm stabilizing drugs on readouts of rhythmic activity, sleep, and cognition in mice. The individual will also conduct end-point measures of efficacy, including immunohistochemical and RNA-Seq based assays. The individual should have experience with in vivo mouse studies, preferably with experience of surgery and telemetric readouts. The individual should possess strong analytical and writing skills.
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