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Postdoctoral Research Fellow

The University of Edinburgh - CMVM - Institute for Regeneration and Repair, Edinburgh University Group - Centre for Inflammation Research

Location: Edinburgh
Salary: £40,247 to £47,874 per annum (Grade 7)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 21st February 2025
Closes: 6th March 2025
Job Ref: 12138

Full-time: 35 hours per week

Fixed term dates: Until 31st January 2026 - it is anticipated that a further extension may be available subject to funder approvals

We are looking for an enthusiastic and ambitious postdoctoral research fellow with interests in neuroimmunology to help us investigate infection as a complication of stroke recovery and the neuroimmune mechanisms that underpin these changes.

This post is advertised as full-time (35 hours per week) and we are open to considering flexible working patterns.

The Opportunity:

We are currently working on understanding the long-term consequences of stroke on the immune system and how this may relate to vulnerability to infection and cognitive outcomes after stroke. This project will use pre-clinical models of stroke combined with vaccination and/ or respiratory infection models. The project will have a focus on the adaptive immune system and include investigations of the impact of stroke on immunological memory and the role of lymphocytes in the recovering brain.

Informal enquiries to Dr Laura McCulloch are welcomed (laura.mcculloch@ed.ac.uk)

The research fellow will be based in the McCulloch lab within the Centre for Inflammation Research (www.ed.ac.uk/inflammation-research). CIR is within the Edinburgh Bioquarter campus which hosts a rich local immunology, neuroscience and vascular community co-located on a major biomedical and health research campus (edinburghbioquarter.com).

Your skills and attributes for success:

  • You will have a PhD (or PhD near completion) or equivalent qualification in a relevant biomedical science and ideally have deep knowledge, interests and skills in neuroimmunology, cerebrovascular disease, respiratory infection or adaptive immune biology 
  • Experience in general in in vivo procedures
  • Experience in immune cell isolation and downstream immunophenotyping e.g. flow cytometry, -omics profiling 
  • Expertise in relevant approaches and models, analytical techniques and methods e.g. immunohistochemistry, microscopy, ELISA, qPCR, statistical approaches
  • Ability to communicate complex information clearly, orally and in writing.
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