Research Associate - Mucus Obstruction in Asthma

Applications are invited for a highly-motivated Research Associate to work on a Medical Research Council funded project to understand mucus obstruction in asthma. In this highly collaborative project involving the Universities of Manchester, Nottingham, Leicester, Imperial College London and AstraZeneca, we aim to advance our understanding of the genetic, molecular and cellular basis of mucus obstruction in the airways of patients with severe asthma. In Manchester in the laboratory of Professor David Thornton, the successful candidate will perform in-depth analysis of respiratory mucins (MUC5AC and MUC5B) and mucus from in vitro and in vivo models, and also collected from the asthma patients. It is highly-desirable that the successful candidate has proven knowledge (evidenced by publications) and experience in respiratory mucus/mucin research including polymeric mucin purification, biochemical/biophysical characterisation, and quantitation, mucus proteomics and primary lung cell air-liquid interface culture.

The project is expected to start on 1^st May 2025 for 4.5 years. Applications are also welcome from candidates wishing to work part-time (minimum 80% time).

What you will get in return:

• Fantastic market leading Pension scheme
• Excellent employee health and wellbeing services including an Employee Assistance Programme
• Exceptional starting annual leave entitlement, plus bank holidays
• Additional paid closure over the Christmas period
• Local and national discounts at a range of major retailers

As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

Our University is positive about flexible working – you can find out more here

Hybrid working arrangements may be considered.

Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.

Any recruitment enquiries from recruitment agencies should be directed to People.Recruitment@manchester.ac.uk.

Any CVs submitted by a recruitment agency will be considered a gift.

Enquiries about the vacancy, shortlisting and interviews:

Name: Dave Thornton

Email: dave.thornton@manchester.ac.uk

General enquiries:

Email: People.recruitment@manchester.ac.uk

Technical support: jobseekersupport.jobtrain.co.uk/support/home

This vacancy will close for applications at midnight on the closing date.