Postdoctoral Scientist - PNAC - Dr Leo James - LMB 2563

3-year fixed term

MRC Laboratory of Molecular Biology, Cambridge, UK

We are looking for a talented postdoctoral researcher with a background in structural biology to join the research team of Dr Leo James. Our work is focused on deciphering the molecular mechanisms driving TRIM21 function and other related TRIM proteins. TRIM21 is a unique intracellular receptor and E3 ligase that targets pathogens and protein aggregates for degradation. Understanding the basis of this activity is essential for defining TRIM21s role in disease and guiding the design of new technologies and therapeutics.

This is a three-year training and development position suitable for you if you have recently completed your doctoral studies, or you are looking to move into a new research discipline and/or need to further develop your research skills. Working with our world class scientists you will be working in an Institute renowned for its excellent scientific facilities and high-quality research.

You will be a highly motivated and dedicated researcher with a desire to understand biology at the molecular level. We offer the opportunity to work alongside like-minded individuals from a variety of backgrounds and to develop your own project whilst contributing to the projects of others. Specifically, you will have a PhD in a relevant subject or be due to complete within six months and existing skills and experience in structural biology, eg cryo-EM, x-ray crystallography, in silico methods, computational biology and biophysics.

The LMB has a collaborative working culture and state-of-the-art building based on the Cambridge Biomedical Campus. We have on-site parking, cycle enclosures and excellent public transport links to the site. We have a staff restaurant with roof terrace and access to a Campus nursery and sports and social facilities. You will be eligible to join our defined benefit pension scheme with an employer contribution of 16%, holiday entitlement of 40.5 days (including bank holidays and privilege days) and a generous employee discount scheme. We are also committed to providing training and development opportunities including support towards role-related qualifications.

The LMB is a world-class research institute within UK Research and Innovation (UKRI). UKRI is nine research councils, working together across all disciplines and sectors. More information can be found at www.ukri.org and www.mrc-lmb.cam.ac.uk.

To apply and access full details of the vacancy please click the 'Apply' button.

If you are unable to apply online please contact us at recruit@mrc-lmb.cam.ac.uk.

Closing date: 11/03/2025

Final appointments will be subject to a pre-employment screening.

We actively support equality, diversity and inclusion in all our activities, processes and culture. We encourage applications from all sections of society. The LMB particularly welcomes women, minority ethnic and disabled candidates to apply for this vacancy as they are currently under-represented. We are a disability inclusive employer and encourage disabled people to apply for this role. You are very welcome to contact us for information about the application process and any adjustments you may require; recruit@mrc-lmb.cam.ac.uk.