Research Fellow in Genome Stability

Hours: Full time.

Requests for flexible working options will be considered (subject to business need).

Location: Brighton, United Kingdom

Contract Type: Fixed term for 3 years

Closing date: Applications must be received by midnight of the closing date.

Expected Interview date: Interviews will be in person, where possible. Or remotely, if not.

Expected start date: As soon as possible.

About the role

The successful applicant will conduct their own research project within the research team. The project will investigate the roles of single-strand break repair proteins (e.g. PARP1, XRCC1) and/or homologous recombination repair proteins (e.g. BRCA1, BRCA2) during DNA repair and DNA replication in human cells, and address how these roles impact on genome stability, cancer, and cancer therapeutics. Also available are projects focused on how XRCC1 protein complexes assemble into a large macromolecular protein complex, and/or how this machine promotes single-strand break repair and prevents human disease.

Based in the School of Life Sciences, the Genome Damage and Stability Centre, a university Centre of Excellence, is an internationally renowned Institute carrying out research on the response of cells to DNA damage, genome instability and its relationship to disease.

About you

The successful applicant/s will have demonstrable expertise in the field of genome stability and/or mammalian/human cell culture. The successful applicant/s will be ambitious, highly motivated, possess excellent time-management and organisational skills, and be able to work effectively both independently and within a team. 

About our School

In the School of Life Sciences we strive to understand the mechanisms that drive biological and chemical processes and to develop innovative and diverse approaches to enhance human health, technology and the environment. We undertake multidisciplinary research, teaching and engagement across a wide range of subjects, from Chemistry through Cellular and Molecular Biosciences to Conservation Biology. 

We pride ourselves on our world-leading research and have a strong research economy, with approximately 50% of our income stemming from research and an active grant portfolio of over £50 million. We host or form part of three University Centres of Excellence: the Genome Damage and Stability Centre, Sussex Neuroscience and Sussex Sustainability Research Programme. In the 2021 Research Excellence Framework, 90.6 % of our Biological Sciences outputs and 84.8% of our Chemistry outputs were rated as world-leading or internationally excellent.

Please find further information regarding the School of Life Sciences on our website.

The School of Life Sciences is proud to hold a Silver Athena Swan Award. 

Why work here

Find out more about our reward and benefits package.

Find out about our equality, diversity and inclusion

Further Key Information

Please first contact Prof. Keith Caldecott (k.w.caldecott@sussex.ac.uk) with an informal enquiry.

The University is committed to equality and valuing diversity, and applications are particularly welcomed from women and black and minority ethnic candidates, who are under-represented in academic posts in Science, Technology, Engineering, Medicine and Mathematics (STEMM) at Sussex.

Please note that this position may be subject to ATAS clearance if you require visa sponsorship.

The University requires that work undertaken for the University is performed in the UK. 

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