Postdoctoral Research Assistant

We are seeking a highly motivated Postdoctoral Research Assistant with expertise and interest in Cell Biology/Physiology/Cardiovascular Science to join the Tzima research group at the Centre for Human Genetics in Oxford. The Tzima research group investigates the role of mechanotransduction in cardiovascular disease and the laboratory is at the cutting edge of developments in in vitro and in vivo models of mechanotransduction. Research projects are highly interdisciplinary, aiming to integrate in vitro biochemical and cell biological techniques with in vivo models and clinical samples. Recent publications from the group include Nature, Science Advances, J Cell Biology. We are looking for a highly motivated Postdoctoral Research Scientist to join the group to work in the area of mechanotransduction, fluidics to characterise the role of a novel gene in atherosclerosis development and progression. You will become part of the Division of Cardiovascular Medicine based at the Centre for Human Genetics in Oxford.

You are required to hold a PhD/DPhil in a relevant discipline and will carry out independent research exploring fundamental mechanisms of mechanotransduction and its role in cardiovascular disease. You will have proven experience in endothelial tissue cell culture, molecular biology techniques including cloning, confocal imaging and biochemical assays (SDS-PAGE and Western blotting, qPCRs). Experience with fluidics systems especially shear stress assays is also required. It is also essential that the applicant has published a first author publication (accepted or in press is also acceptable) that is not a review.

This is a full time appointment on a fixed term contract for 1 year with the possibility of extending, and you will be based at the Centre for Human Genetics, Old Road Campus, Roosevelt Drive, Oxford, OX3 7BN.

Applications for this vacancy are to be made online; you will be required to upload a CV and supporting statement which explains how you meet the selection criteria for the post.

Only applications received before 12.00 midday on Friday April 4th can be considered. Interviews are scheduled to place the week of April 14th.

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