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Research Assistant in Cancer Biology

University of Oxford - Centre for Human Genetics, Building for Genomic Medicine

Location: Oxford
Salary: £34,982 to £37,630 per annum : Research Grade 6. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 6th February 2025
Closes: 6th March 2025
Job Ref: 178054

 We are seeking to appoint an enthusiastic and motivated Research Assistant to assist with the molecular characterisation of human tumours and maintenance and analysis of model systems we have generated in our laboratory. The post will focus principally on the mechanisms and consequences of immune escape in colorectal and endometrial cancers, thought there will be flexibility to contribute to other projects. This role extends the longstanding interest of our group in genomic instability and tumour immunology including our recent work in this area (Cornish et al. Nature, Frei et al. Lancet Oncology, Glaire et al. J Pathol), and will synergise with the LynchVax and GO-PRECISE CRC-VAX projects which are led or co-led by the Principal Investigator.

You will be responsible for undertaking laboratory work as required in molecular and functional genetics, such as sample preparation, genotyping, mutation screening, and analysis of tumours, cell culture, and genetic manipulation. You will also collate basic output data in a format for use by analysts and others within the group, undertake quality control and preparing data for review and statistical analysis, and collate and present data for other laboratory work, such as Home Office returns for mouse procedures (if appropriate). Undertaking other duties as required within the general area of the laboratory’s projects, commensurate with the grade and responsibilities of this post, taking accountability for your professional conduct within the Group and the Centre, and ensuring that all conduct is with due regard to the University Equal Opportunities and Data Protection policies are also essential to the role.

It is essential that you hold a degree in a relevant subject and have demonstrable academic and technical ability. Commitment to high standards, including record keeping, ability to learn rapidly and to master several techniques, and good written and electronic communication skills are essential to the role. It is essential you possess sufficient specialist knowledge in the discipline to work within established research programmes, and will have excellent communication skills, including the ability to write text that can be published, present data at conferences, and represent the research group at meetings. Demonstrable interest in medical research is highly desirable.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This position is offered full time on a fixed term contract for 3 years and is funded by Cancer Research UK.

Only applications received before 12 midday on 6 March 2025 will be considered. Please quote 178054 on all correspondence.

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