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Research Laboratory Technician (Fixed Term)

University of Cambridge - Department of Medicine

Location: Cambridge
Salary: £30,505 to £34,866 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 30th January 2025
Closes: 27th February 2025
Job Ref: RC43739

We are seeking an enthusiastic Research Laboratory Technician to join our research programme investigating the causes and mechanisms of human immune deficiency. The technician will join the Intrepid (Integrative Translational Research in Primary Immune Deficiency) project, which was established to refine and enhance the use of whole genome sequencing both as a diagnostic tool in the clinic, and to advance understanding of the genetics of primary immune deficiency. Intrepid is funded by a Wellcome Trust Collaborative Award.

The appointed technician will be based in the Cambridge Institute for Therapeutic Immunology and Infectious Disease and be supervised by one or more of the Intrepid Principal Investigators.

The successful candidate must hold a degree in a related biological sciences discipline, as well as laboratory experience in molecular biology and/or immunology. The post-holder will primarily engage in experiments to characterize the function of genetic variants identified through whole genome sequencing, which may contribute to immune diseases. A strong foundation in molecular biology techniques, including cloning and gene expression in cell lines, is essential. Additionally, proficiency in analyzing these variants using flow cytometry and Western blotting is required. The role may also involve employing CRISPR/Cas9 gene editing to manipulate specific genetic variants and assess their effects on immune response.

Candidates should also demonstrate evidence of being able to effectively troubleshoot research problems and adapt research protocols. A meticulous and orderly approach to laboratory work, excellent organisational skills and the ability to work as part of a team, as well as independently, are essential. We are looking for a colleague who excels in a multidisciplinary team environment and is committed to working collaboratively to achieve the experimental objectives of the project.

This position is full-time fixed-term until the end of August 2026.

For an informal discussion about this post, please contact Professor Matthew Cook (mc2386@cam.ac.uk)

The role is available for an immediate start and we will be looking to interview shortly after the closing date.

Fixed-term: The funds for this post are available until 30 August 2026 in the first instance.

To apply online for this vacancy and to view further information about the role, please click the 'Apply' button above. 

Please ensure that you outline how you match the criteria for the post and why you are applying for this role on the online Application form.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

The closing date for applications is: 27th February 2025

The interview date for the role is: To be confirmed

Please quote reference RC43739 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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