Research Fellow

About us

Biosciences is one of the world’s foremost centres for research and teaching in the biological sciences and one of the largest Divisions within UCL, undertaking a significant amount of research and teaching. The Division has a diverse portfolio addressing all areas of biology from protein interactions to cell function, organism development, genetics, population studies and the environment. Computational modelling approaches are frequently used alongside experimental research programmes and much of our research crosses traditional boundaries, including the relationship of biodiversity to the health of the planet. Activity is underpinned by high calibre science technology platforms and state of the art equipment. Educational activity includes a range of undergraduate programmes, an expanding number of Masters Programmes and a substantial number of postgraduate research students. This is an exciting opportunity to join the RN AP laboratory at the Institute for Structural and Molecular Biology at UCL. Our research is focussed on the structure, function and evolution of gene expression in archaea. This research program is about the coupling of transcription and translation in Sulfolobus, and we are seeking three enthusiastic, knowledgable and hard-working individuals to push the frontiers of science!

About the role

The main purpose of this position is to carry out cutting edge research. The team for this project includes a biochemist, a structural biologist, and a systems biologists with experience in functional genomics. The three will work as closely knit team in a multidisciplinary fashion, taking ownership of their project and happy to collaborate.

Your research will focus on integrated structural biology approaches to study transcription in archaeal organisms including:

1. Extensive experience with the production of recombinant proteins
2. Biomolecular structure determination
3. cryo-Electron Microscopy
4. cryo-Electron Tomography
5. X-ray crystallography
6. Preferably published in the fields of transcription or translation.

This role is an open-ended contract with a funding end date of 28/02/2030 in the first instance.

Research Fellows - 'Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Grade 6B (salary £34,502 - £36,348 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD Thesis.'

This appointment is subject to UCL Terms and Conditions of Service for Research and Professional Services Staff. Please visit https://www.ucl.ac.uk/human-resources/conditions-service-research-teaching-and-professional-services-staff for more information.

If you need reasonable adjustments or a more accessible format to apply for this job online or have any queries about the application process, please contact Biosciences staffing at .

About you

You will need the following skills and experience:

1. Proven trackrecord in recombinant protein purification and handling for structural analyses
2. Proven trackrecord in biomolecular structure determination using X-ray crystallography, cryo-Electron Microscopy and cryo-Electron Tomography
3. Robust experience working with complex molecular machines in vitro and in vivo
4. Preferably published well in the fields of transcription or translation

Customer advert reference: B02-08082

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