Postdoctoral Fellow

Short summary

We are looking for a Postdoctoral Researcher to join the Cancer Dynamics Laboratory and undertake a range of mathematical and computational modelling projects. The Postdoctoral Fellow is expected to integrate the modelling work closely with diverse research activities in the lab, such as genomic and spatial phenotyping of patient samples from the TRACERx Renal study as well as patient-derived organoid and tissue fragment experiments in vitro.

This exciting Postdoctoral position will contribute to MANIFEST (“Multiomic ANalysis of Immunotherapy Features Evidencing Success and Toxicity”), a newly formed ambitious multi-stakeholder consortium involving academic, industry and NHS partners to deliver deep multi-omic profiling for patients with cancer undergoing immunotherapy. The MANIFEST consortium represents a diverse group of UK-wide experts in cancer research and clinical care comprising major NHS trusts, academic institutes and universities, and industry partners. This grant is funded by the UK Office of Life Sciences and the Medical Research Council.

Key Responsibilities

Include but not limited to:

• Spearheading their project on the development of mathematical and computational models to study spatial immune microenvironment and response to immunotherapy.
• Management of collaboration with other group members and collaborators working on spatial biology and multimodal data integration.
• Regular meetings with Samra and Xiao to discuss research plans and progress.
• Presentations of research at Samra’s and Xiao’s lab meetings, MANIFEST Consortium meetings, and Cancer Interest Groups and other relevant events at the Crick.
• Writing and presenting work to MANIFEST stakeholders as required.
• Engaging in relevant MANIFEST programme workflows with academic, NHS and industry partners.

Postdoctoral Fellows are expected to lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and guide PhD students in their research. The ability to work in a team is essential.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council, Cancer Research UK, Wellcome, UCL, Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

• If you are interested in applying for this role, please apply via the ‘Apply’ button above.
• All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

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