Research Assistant/Associate - Regulation of Gene Expression

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

Salary
Research Assistant £32,296 to £33,882 per annum.
Research Associate £34,866 per annum.

The Role
This post is an exciting opportunity for a Research Assistant/Associate to work on a new project investigating the molecular mechanisms of cardiovascular disease during prostate cancer therapy. The project is funded by the JGW Patterson Foundation and is aimed at generating pilot data to support further funding applications.

We are looking for a motivated researcher to join our group to perform transcriptomics and functional assays in human cardiomyocytes treated with prostate cancer hormone therapy drugs.

In this role, you will be based at our Newcastle Upon Tyne campus that has fantastic transport links and state of the art facilities. You will be a member of the Newcastle University Biosciences Institute (https://www.ncl.ac.uk/medical-sciences/research/institutes/biosciences/) as well as the ‘Cells, Genes and Molecules' and the ‘Vascular Biology and Medicine' research themes (https://www.ncl.ac.uk/medical-sciences/research/research-themes/).

You will work with a highly collaborative and diverse team of RNA biologists, as well as vascular and cancer researchers based in Newcastle, Leeds and Sheffield.

This project will provide an opportunity to develop and expand the fast-growing research area of cardio-oncology, with a unique angle on nuclear biology. You will acquire skills in cellular and molecular biology while gaining knowledge in a multidisciplinary research area, and there will be a possibility to learn basic bioinformatics skills on your own data.

What do we need from you?

To apply for the position, you’ll provide your CV and a covering letter outlining how you are suitable for the role using examples to highlight how you meet the essential criteria in the knowledge, skills and experience as listed in the job description (available on the university's website, accessed by the 'Apply' button).

Please focus your cover letter on the following key areas, outlining your proven ability and experience with:

• Regulation of gene expression, especially RNA transcription and processing.
• Molecular biology techniques such as nucleic acid extraction, PCR-based methods and Western blotting.
• Mammalian cell culture (ideally including drug treatment and nucleic acid transfection).
• Leading the experimental planning and coordination of a laboratory-based research project.

This post is fixed-term for a period of 12 months.

If you have any questions prior to applying, please contact Dr Sara Luzzi (sara.luzzi@newcastle.ac.uk).

Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/.

Find out more about our Research Institutes here: https://www.ncl.ac.uk/medical-sciences/research/institutes/.

As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

Please note that if you are successful to this role, you will require a DBS and a medical clearance before you can commence in the role.

Advert information