PhD Studentship: The temporal dynamics of higher-order gene regulation in plant immunity BBSRC SWBio DTP PhD studentship 2025 Entry
University of Exeter - Biosciences
| Qualification Type: | PhD |
|---|---|
| Location: | Devon, Exeter |
| Funding for: | UK Students, EU Students, International Students |
| Funding amount: | Up to £19,237 annual stipend |
| Hours: | Full Time |
| Placed On: | 19th November 2024 |
|---|---|
| Closes: | 11th December 2024 |
| Reference: | 5330 |
About:
The BBSRC-funded SWBio DTP involves a partnership of world-renown universities, research institutes and industry, based mainly across the South West and Wales.
This partnership has established international, national and regional scientific networks, and widely recognised research excellence and facilities.
We aim to provide you with outstanding interdisciplinary bioscience research training, underpinned by transformative technologies.
Project Description
Every year, more than 20 % of agricultural productivity is lost due to plant diseases caused by pathogens. An essential element for the plant to effectively counteract pathogen attack is the ability to precisely control the expression of its defence-related genes. Regulation of gene expression, switching genes on and off, is a process that is generally modulated on different molecular levels. A higher level of gene regulation, the epigenetic and topological organisation of chromosomes, has only recently been recognised as playing an important role in gene expression. Dynamic changes to the epigenetic modification of chromatin and the three-dimensional folding of chromosomes were linked to the differential regulation of individual genes, defined genomic regions and large chromosomal territories.
How the temporal dynamics of plant immunity gene expression is regulated on this level is largely unexplored. Yet, understanding its mechanism will expand our fundamental knowledge about plant defence and reveal novel paths to enhance the resilience of plants against pathogens.
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