PhD Studentship: The Role of Zinc in the Adaptation of Diatoms to Conditions of Polar Oceans

Scientific background  

Diatoms are the main primary producers in polar oceans, where photosynthesis is largely limited by seasonal fluctuation in light, temperature and the extent of sea ice. Additionally, essential trace metals such as iron and zinc play an important role in controlling the biomass of polar primary producers. Polar diatoms appear to have a particularly high demand for zinc, thereby largely determining zinc distribution throughout the global ocean. The reason for the enhanced requirement of zinc in polar diatoms remains enigmatic. However, the first genome sequences from a polar diatom and other cold-adapted algae revealed adaptive expansions of gene families containing zinc-binding domains. The elevated concentrations of zinc in polar oceans may thus have aided the expansion of these zinc-binding domains. As specific gene families involved in photosynthesis and carbon fixation were both co-expanded and co-expressed, it suggests that zinc plays an important role in supporting photosynthetic growth in polar phytoplankton.   

Research methodology  

The main aim of this project is to produce the first molecular genetics and biochemical data on the role of zinc in the physiological adaptation of cold-adapted diatoms. You will work in the laboratory with a cold-adapted model diatom and will apply the latest reverse genetics tools (e.g. CRISPR-Cas) in combination with sequencing (RNA/DNA) and photosynthesis measurements (e.g. carbon acquisition, quantum yield) to characterise to role of conserved low-temperature inducible regulatory genes with zinc-binding domains (e.g. zf-MYND) that are co-regulated with photosynthesis genes. A combination of these experimental approaches together with an evolutionary analysis will provide first insights into the role of zinc-binding domains in supporting photosynthesis in polar marine microalgae.   

Training  

You will gain skills in the latest reverse-genetics tools such as CRISPR-Cas and sequence analyses, algal cultivation, photosynthesis measurements, protein biochemistry, bioinformatics and evolutionary biology.   

Person specification  

A degree in Biological Science or equivalent. We are looking for an enthusiastic student who is excited about applying diverse techniques from the field of molecular microbiology to understand the adaptation and evolution of microalgae in polar oceans,

Entry Requirements

The minimum entry requirement is 2:1 in a Bachelor’s degree in Biological Sciences or equivalent.

Start date: 1 October 2025

Funding Details

Additional Funding Information

ARIES is awaiting confirmation of funding under the BBSRC-NERC DLA award scheme, which is expected shortly. Funding for this studentship is subject to this confirmation and UKRI terms and conditions. Successful candidates who meet UKRI’s eligibility criteria will be awarded a fully-funded ARIES studentship of fees, maintenance stipend (£19,237 p.a. for 2024/25) and research costs. 

A limited number of ARIES studentships are available to International applicants. Please note however that ARIES funding does not cover additional costs associated with relocation to, and living in, the UK. 

ARIES is committed to equality, diversity, widening participation and inclusion in all areas of its operation. We encourage applications from all sections of the community regardless of gender, ethnicity, disability, age, sexual orientation, and transgender status. Projects have been developed with consideration of a safe, inclusive, and appropriate research and fieldwork environment. Academic qualifications are considered alongside non-academic experience, with equal weighting given to experience and potential. 

For further information, please visit www.aries-dtp.ac.uk 

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