Research Associate position in regulatory T cell biology in autoimmunity

About the role:

This Research Associate position is funded by the Multiple Sclerosis (MS) Society UK for 36 months to investigate the mechanisms underlying the defective function of follicular regulatory T cells (Tfr) in people living with multiple sclerosis. The candidate will join Dr Dominguez-Villar’s laboratory at Imperial College London, which focuses on understanding the molecular mechanisms that maintain human regulatory T cell identity and plasticity and the regulation of CD4⁺ T cell responses in autoimmune and infectious diseases.

What you would be doing:

We are looking for a passionate, self-motivated and committed postdoctoral research associate with expertise in in vitro T cell and Treg culture, as well as expertise in in vivo mouse models of multiple sclerosis (EAE).

What we are looking for:

• PhD in immunology or related discipline.
• Practical experience in high parameter flow cytometry.
• Practical experience in T cell and Treg isolation, culture and in vitro assessment of functions.
• Practical experience in in vivo models of multiple sclerosis including immunization, monitoring, evaluation, organ dissection.
• Knowledge of basic cellular and molecular mechanisms in immune responses.
• Knowledge of statistical analysis tools. 

What we can offer you:

• The opportunity to be part of an exciting project with translational potential, using both mouse models and samples from patients.

• The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.
• Grow your career: Gain access to Imperial’s sector-leading dedicated career support for researchers as well as opportunities for promotion and progression

• Sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes).

Further Information

Expected start date is January 2025 or as soon as possible thereafter.

If you require any further details on the role please contact Dr Margarita Dominguez-Villar (m.dominguez-villar@imperial.ac.uk)

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