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Advanced Research Fellow

University of Aberdeen - Medicine, Medical Sciences & Nutrition - Institute of Medical Sciences

Location: Aberdeen
Salary: £45,585 to £49,794 (Grade 7)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 2nd August 2024
Closes: 16th August 2024
Job Ref: IMS288R

Funding limited for 35 months. 

Applications are invited for a an experienced, skilled, and ambitious postdoctoral research associate to join the team of Dr. Jenna Gregory in the Institute of Medical Sciences (IMS) at the Foresterhill campus of the University of Aberdeen, to undertake innovative research into the role and distribution of TDP-43 misfolding across motor networks in amyotrophic lateral sclerosis (ALS).

We are seeking candidates with a mix of wet and dry lab expertise. Wet lab skills will be handling mouse and human tissue and applying the molecular techniques including BaseScope, immunohistochemistry and histological special stains. Dry lab skills will be primarily analytical and statistical (handling complex datasets such as integrating clinical and experimental data) and digital image analysis (QuPath/Cell profiler).

Key responsibilities include; 1) the design of experiments to investigate the role and distribution of TDP-43 pathology across motor networks, 2) the generation of data from molecular wet-lab experiments and investigations, 3) the analysis of datasets arising from experiments and investigations, and 4) contributing to ongoing research in the in the group including bench supervision and support of students.

The successful applicant will hold a PhD-level degree in biological/medical sciences or a related relevant topic. Candidates with a broad skill set spanning wet-laboratory, and data analytical approaches are encouraged to apply.

Knowledge of molecular techniques and technologies are essential, with emphasis on skills in immunohistochemistry, RNA ISH, and histological staining, along with experience and/or familiarity with digital image analysis (e.g. using QuPath or similar). Strong data science skills i.e., data analysis and statistics are essential. Research experience in neuroscience, ALS, and/or other neurodegenerative diseases is very desirable. Applicants should have experience in the design, analysis, and publication of experiments, with a willingness to supervise students and engage with laboratory management tasks.

Salary will be at the appropriate point on the Grade 7, £45,585 – £49,794 per annum, and negotiable with placement according to qualifications and experience.

Informal enquiries should be made to Dr. Jenna Gregory, Senior Clinical Lecturer and Consultant Histopathologist (01224 437524 / Jenna.gregory@abdn.ac.uk).

Prior to employment, the successful candidate must be able to demonstrate their right to work in the UK.  This role may be eligible for sponsorship under the Skilled Worker route under the UKVI immigration rules but is dependent on factors specific to the candidate and if tradeable points can be used under the rules.

Information on other visa options is available at www.gov.uk/check-uk-visa.

Please do not hesitate to contact Grant Rae, HR Adviser (e-mail: grant.rae@abdn.ac.uk) for further information.

To apply online for this position visit www.abdn.ac.uk/jobs

The School of Medicine, Medical Sciences and Nutrition embraces a diverse working environment and recognises the many benefits this can bring.  Applications from individuals from across all of the equality protected characteristics are encouraged.

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